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Job Description
Molecule and BIO.xyz are building the foundation of Decentralized Science (DeSci) — where biotech meets web3 to make scientific research community-owned, transparent, and faster to market. Molecule provides the infrastructure to turn intellectual property (IP) into programmable, on-chain assets through our IP-NFT framework and evolving protocol stack. This enables researchers, patients, and communities to fund and govern biotech projects in new, open ways. BIO.xyz is the coordination and economic layer of DeSci, powering BioDAOs through funding, governance, and ecosystem alignment. Together, we are creating a new model for scientific discovery — one where breakthroughs are owned and advanced by the communities that believe in them. Location: Germany (lab site TBC - right candidate informs final location) Type: Senior IC role - no team to manage on day one; you hire your team in year two once the proof exists The Role Capsules. Tablets. Sterile compounding. We're building precisely-dosed formulations of cognitive, performance, and longevity compounds - modafinil, bromantane, GLP-1 analogs, BPC-157, thymosin α-1, and a growing pipeline of small-molecule and peptide actives. You will set our formulation standards, run the bench work, and be the person who can defend every excipient choice, every dissolution curve, and every sterility result. From active properties to qualified drug product - oral, injectable, topical - with documentation that holds up. What You'll Do Design oral solid-dose formulations (capsules and tablets) from active properties up - excipient selection, diluents, binders, disintegrants, flow agents, and lubricants matched to each compound's solubility, stability, and dosing profile Design sterile injectable formulations for our peptide pipeline - lyophile design, bulking agents, cryoprotectants, vial fill/finish at small scale, reconstitution protocols, and container-closure compatibility. Hands-on with EU GMP Annex 1 (sterile manufacturing) and applicable AMG/AMWHV requirements Own encapsulation, blending, and aseptic processing end to end: powder characterization, blend uniformity, content uniformity, capsule fill weight control, scale-up from bench to production batches, and sterility assurance for the injectable side Solve hard actives. Bromantane and modafinil bring oral-side challenges - low aqueous solubility, poor flow, dose accuracy at small fill weights. Peptides like BPC-157, GLP-1 analogs, and GHK-Cu bring injectable-side challenges - stability across the lyophile/reconstitution cycle, copper-complex integrity, peptide aggregation. You develop the techniques that make all of them reproducible Build and run the analytical backbone: dissolution testing, assay/potency, content and weight uniformity, sterility (Ph. Eur. 2.6.1), endotoxin (Ph. Eur. 2.6.14), and stability programs (ICH Q1A - accelerated and long-term) to establish shelf life Write documentation that holds up: master formulation records, batch records, speci